Qiangwei Peng (彭强威)

Qiangwei Peng (彭强威)

Focus on single-cell spatiotemporal dynamics modeling and construction of virtual cells

🐾 About Me

I am currently working on spatiotemporal dynamics modeling and perturbation response modeling of single-cell and spatial transcriptomics data. If you are interested in academic collaboration, please feel free to email me at qiangwei_peng@stu.pku.edu.cn.

I am a fifth-year Ph.D. student in the School of Mathematical Sciences, Peking University, advised by Prof. Tiejun Li (李铁军). Previously, I was a visiting student researcher in the Department of Genetics, Stanford University, working with Prof. Xiaojie Qiu (邱肖杰). I received my B.Sc. in Mathematics from Xiamen University, mentored by Prof. Wen Huang (黄文), and also earned a second bachelor’s degree in Economics.

My research lies at the intersection of mathematics, computational biology, and deep generative modeling. I develop mathematical and deep learning frameworks to reconstruct continuous cellular dynamics from single-cell and spatial transcriptomics data, and to model perturbation-response dynamics for building virtual cells.

Ultimately, I aim to enable predictive modeling of early developmental processes — from a single fertilized egg to a fully formed embryo. By creating virtual embryos, I hope to perform in silico experiments that complement or even replace traditional wet-lab approaches, advancing our understanding of developmental biology.

🔥 News

  • 2025.10:  🎉🎉stVCR was accepted by Nature Methods! It is the first algorithm that can reconstruct continuous spatiotemporal dynamics from spatial transcriptomic snapshots, including gene expression changes, spatial migration, and cell proliferation.
  • 2024.6:  🎉🎉 We submitted the preprint of stVCR.
  • 2024.11:  🎉🎉 Storm was accepted by PLOS Computational Biology! We designed a stochastic dynamics model for the metabolic labeling scRNA-seq data.
  • 2023.11:  🎉🎉 My first paper was published in Inverse Problems! We proposed a regular-texture image inpainting method based on exemplar matching and low-rank sparse prior.

📝 Publications

🎖 Honors and Awards

  • 2025.09  🎓 Peking University May Fourth Scholarship
  • 2025.09  🏅 Peking University Merit Student
  • 2025.06  🎓 Peking University President’s Scholarship
  • 2022.12  🏅 Peking University Excellence in Research Award
  • 2021.06  📘 National Program for the Cultivation of Top Students in Mathematics (Ministry of Education)
  • 2021.06  🎓 Outstanding Graduate of Xiamen University
  • 2020.11  🥈 Second Prize (National Level), China Undergraduate Mathematical Contest in Modeling (CUMCM)
  • 2020.10  🏅 Outstanding Award in Computational and Applied Mathematics Category, S.-T.Yau College Student Mathematics Contests

📖 Educations

  • 2021.09 - Present, Ph.D. Candidate, School of Mathematical Sciences, Peking University
  • 2025.03 - 2025.08, Visiting Student Researcher, School of Medicine, Stanford University
  • 2019.02 - 2021.06, Bachelor’s Degree (Double Major), School of Economics, Xiamen University
  • 2018.09 - 2021.06, Bachelor’s Degree, School of Mathematical Sciences, Xiamen University
  • 2017.09 - 2018.09, Undergraduate Student (Transferred), College of Physical Science and Technology, Xiamen University

💬 Invited Talks

  • 2025.03, Poster presentation at APS March Meeting, American Physical Society
  • 2024.10, Outstanding Poster, The 22nd Annual Conference of CSAIM (China Society for Industrial and Applied Mathematics)
  • 2024.08, Contributed talk in a parallel session at the 15th International Conference on Computational Systems Biology (ISB 2024)
  • 2023.10, Contributed talk in a parallel session at the 3rd Conference on Mathematical Life Sciences

📚 Teachings

  • 2021 – 2024, Teaching Assistant for the following courses at Peking University:
    • Linear Algebra
    • Calculus
    • Stochastic Simulation Methods